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Thoracic Wall Nerve Block and Postoperative Atrial Fibrillation in Cardiac Surgery: A Target Trial Emulation Study

Thoracic Wall Nerve Block and Postoperative Atrial Fibrillation in Cardiac Surgery: A Target Trial Emulation Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0011981
Enrollment
3000
Registered
2026-05-14
Start date
2026-05-25
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Asan Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients who underwent cardiac surgery between July 1, 2023, and December 31, 2025. Only electronic medical records that had already been collected by April 19, 2026, including the follow-up period, were reviewed.

Exclusion criteria

Exclusion criteria: Age < 18 years History of atrial fibrillation Use of antiarrhythmic medications other than beta-blockers within 2 weeks prior to surgery Patients with a previously implanted permanent pacemaker (PPM) or implantable cardioverter-defibrillator (ICD) Emergency cardiac surgery Critically ill patients requiring mechanical circulatory support (MCS) or pharmacological circulatory support preoperatively Patients deemed inappropriate for study inclusion at the investigators' discretion

Design outcomes

Primary

MeasureTime frame
in-hospital Postoperative Atrial Fibrillation

Secondary

MeasureTime frame
Composite outcome of in-hospital postoperative atrial fibrillation (POAF) or all-cause in-hospital mortality. The event is defined as the occurrence of either component; each component (POAF and mortality) is also analyzed individually to assess the validity of the interpretation.;Cumulative opioid consumption within 12 hours after surgery, expressed as Morphine Milligram Equivalents (MME). All intravenous and oral opioids documented in the medical records are converted to MME using standard conversion factors and summed.;Performance of direct current cardioversion (DCCV) for in-hospital postoperative atrial fibrillation, ascertained by medical record review.;Time from the end of surgery to tracheal extubation in the intensive care unit or recovery room (in hours), assessed by medical record review.;Occurrence of postoperative delirium during the in-hospital period, defined as a delirium diagnosis documented by the clinical team or a positive assessment using a standardized tool (e.g., Confusion Assessment Method for the Intensive Care Unit, CAM-ICU) recorded in the medical records.;Length of stay in the intensive care unit (ICU), measured from ICU admission after surgery to transfer to the general ward, ascertained by medical record review.;Total hospital length of stay (HLOS) measured in days, from the date of surgery to the date of hospital discharge.

Countries

Korea, Republic of

Contacts

Public ContactChangjin Lee

Asan Medical Center

daskrnr@naver.com+82-2-3010-1005

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: May 22, 2026