Study on the Effects of Oral Colostrum Application to Strengthen Immunity in Preterm Infants

Effects of Oropharyngeal Administration of Colostrum in Preterm Infants

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011980

Enrollment

Registered

2026-05-14

Start date

2017-03-21

Completion date

Unknown

Last updated

2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(Nurse-led Oropharyngeal Administration of Colostrum) : 1. Experimental Group Intervention Name: Oropharyngeal Administration of Colostrum (OAC) Dosage & Frequency: 0.2 mL of mother's own colost

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Infants born with a birth weight of less than 1,500g. Infants with no congenital anomalies. Infants whose legal guardians (parents) understood the purpose of the study and provided written informed consent for participation.

Exclusion criteria

Exclusion criteria: Infants with congenital anomalies. Infants with gastrointestinal or renal diseases. Infants of mothers who are taking medications contraindicated for breastfeeding, such as those with HIV.

Design outcomes

Primary

Measure	Time frame
Salivary Secretory Immunoglobulin A (sIgA) Levels;Antibiotic use;Days of Feeding Intolerance ;time to Full Enteral Feeding(PCA, weeks);time to Full Oral Feeding (PCA, weeks)	—

Secondary

Measure	Time frame
NEC Incidence (Mean Rank);CRP Levels;Birth weight recovery date	—

Countries

Korea, Republic of

Contacts

Public ContactHyunyoung Seo

Ulsan College

hyseo@uc.ac.kr+82-52-230-0732

Outcome results