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Effect of intravenous acetaminophen on emergence agitation after general anesthesia for nasal surgery: a prospective, randomized, assessor-blinded, placebo-controlled trial

Effect of intravenous acetaminophen on emergence agitation after general anesthesia for nasal surgery: a prospective, randomized, assessor-blinded, placebo-controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0011904
Enrollment
112
Registered
2026-04-27
Start date
2026-05-18
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Prior to the conclusion of surgery, the treatment group will receive intravenous acetaminophen 1 g/100 mL administered over 15 minutes, while the control group will receive 0.9% normal saline 1

Sponsors

Konyang University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adults aged 19 to 65 years ASA physical status classification I or II Patients scheduled to undergo nasal surgery under general anesthesia Patients scheduled for endotracheal intubation Patients who have voluntarily provided written informed consent

Exclusion criteria

Exclusion criteria: Patients with contraindications to acetaminophen use (hepatic dysfunction, severe hepatic disease, etc.) Patients with obstructive sleep apnea Patients with cognitive impairment Patients undergoing emergency surgery Patients scheduled for postoperative transfer to the intensive care unit (ICU) Patients with alcohol or drug dependence Pregnant or breastfeeding women Patients who do not consent to study participation

Design outcomes

Primary

MeasureTime frame
Incidence of emergence agitation

Secondary

MeasureTime frame
Hemodynamic variables including heart rate and blood pressure;Time from discontinuation of anesthetic agent to extubation,;type and dose of analgesics administered in the post-anesthesia care unit;ncidence of postoperative nausea and vomiting (PONV)

Countries

Korea, Republic of

Contacts

Public ContactKIM YOUSEOK

Konyang University Hospital

dongb180@hanmail.net+82-42-600-9317

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: May 7, 2026