None listed
Conditions
Interventions
None listed
Sponsors
The Catholic University of Korea, Eunpyeong St. Mary's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult patients scheduled for orthopedic shoulder surgery 2. Patients undergoing an ultrasound-guided interscalene brachial plexus block for perioperative analgesia before surgery 3. Patients receiving an interscalene brachial plexus block with either 0.5% ropivacaine or 0.25% ropivacaine as part of routine clinical practice 4. Patients able to undergo ultrasound elastographic assessment of the C5 nerve root before the block, immediately after the block, and 20 minutes after the block 5. Patients able to undergo cold sensation testing in the relevant dermatome at 20 minutes after the block 6. Patients who voluntarily provide written informed consent after receiving a full explanation of the study purpose and procedures
Exclusion criteria
Exclusion criteria: 1. Patients who decline participation or are unable to provide written informed consent 2. Patients with known hypersensitivity or allergy to ropivacaine or other amide-type local anesthetics 3. Patients with local infection at the intended block site or clinically significant systemic infection 4. Patients with pre-existing sensory deficit, motor deficit, peripheral neuropathy, cervical radiculopathy, or other neurologic abnormality in the operative upper limb or neck that may interfere with interpretation of C5 nerve root stiffness or sensory testing 5. Patients who are unable to understand or cooperate with the study procedures, making serial ultrasound assessment and sensory evaluation unreliable 6. Patients considered unsuitable for the planned interscalene brachial plexus block by the attending anesthesiologist because of current bleeding risk, coagulopathy, or antithrombotic medication status 7. Patients with clinically significant respiratory insufficiency, or those otherwise judged unsuitable for interscalene brachial plexus block by the attending anesthesiologist 8. Patients in whom the block is performed with a concentration or volume different from the study protocol, or who receive additional peripheral nerve block(s) before the primary assessment at 20 minutes 9. Patients for whom reliable measurement or interpretation of the primary outcomes is judged to be difficult by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak pain score at rest on postoperative day 1 | — |
Secondary
| Measure | Time frame |
|---|---|
| Loss of cold sensation in the relevant dermatome at 20 minutes after interscalene brachial plexus block;Peak pain score during PACU stay;Cumulative rescue analgesic consumption during PACU stay;Use of rescue antiemetics during PACU stay;Cumulative analgesic consumption on postoperative day 1, including IV PCA use and rescue analgesics;Change in C5 nerve root stiffness from baseline to 20 minutes after interscalene brachial plexus block | — |
Countries
Korea, Republic of
Contacts
Public ContactMinsuk Chae
The Catholic University of Korea, Eunpyeong St. Mary's Hospital
Outcome results
None listed