Effect of an Exercise Program on Metabolic Syndrome in Endometrial Cancer Patients after Oophorectom

Effect of a Structured Exercise Program on Metabolic Syndrome in Endometrial Cancer Patients after Oophorectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011862

Enrollment

Registered

2026-04-16

Start date

2026-04-27

Completion date

Unknown

Last updated

2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Behavioral : Participants will be randomly assigned in a 1:1 ratio to either an exercise group or a control group. The exercise intervention will last 12 weeks and will consist of supervised resistanc

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: • Women aged 19 to 54 years • Diagnosed with endometrial cancer • Underwent oophorectomy • Stage I to III disease • Within 12 months after surgery • At possible status of surgical menopause • Able to visit the Yonsei University fitness center at least once weekly • Physically able to participate in physical activity and exercise • Native Korean speaker and able to read Korean

Exclusion criteria

Exclusion criteria: • Age 55 years or older • Stage IV or higher endometrial cancer • Planned reoperation due to infection • Diagnosed with endometrial cancer but did not undergo oophorectomy • History of diagnosed or treated psychiatric disorders such as depression or anxiety • Severe musculoskeletal, cardiovascular, or internal medical disease • Limitation in exercise participation due to delayed postoperative recovery • Considered inappropriate for study participation due to past or current medical history or medication use

Design outcomes

Primary

Measure	Time frame
Metabolic syndrome severity score	—

Secondary

Measure	Time frame
Metabolic syndrome indicators;Maximal oxygen uptake;Estimated one-repetition maximum for chest press, leg press, and leg extension;Glycated hemoglobin level;Total cholesterol level;Triglyceride level;C-reactive protein level;Quality of life assessed by EORTC QLQ-C30 and EORTC QLQ-EN24;Physical activity assessed by the Global Physical Activity Questionnaire;Cognitive function assessed by the Mini-Mental State Examination;Mediterranean diet adherence assessed by KMEDAS;Height, body weight, body fat mass, percent body fat, skeletal muscle mass, body mass index, waist circumference, and blood pressure;Body composition and bone-related measures assessed by dual-energy X-ray absorptiometry	—

Measure

Time frame

Metabolic syndrome indicators;Maximal oxygen uptake;Estimated one-repetition maximum for chest press, leg press, and leg extension;Glycated hemoglobin level;Total cholesterol level;Triglyceride level;C-reactive protein level;Quality of life assessed by EORTC QLQ-C30 and EORTC QLQ-EN24;Physical activity assessed by the Global Physical Activity Questionnaire;Cognitive function assessed by the Mini-Mental State Examination;Mediterranean diet adherence assessed by KMEDAS;Height, body weight, body fat mass, percent body fat, skeletal muscle mass, body mass index, waist circumference, and blood pressure;Body composition and bone-related measures assessed by dual-energy X-ray absorptiometry

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Countries

Korea, Republic of

Contacts

Public ContactSusanna Jun

Yonsei University

sallysanna@gmail.com+82-2-2123-6197

Outcome results