None listed
Conditions
Interventions
None listed
Sponsors
Keimyung University Dongsan Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Adults aged 19 years or older at the time of providing written informed consent 2.Patients diagnosed with non-valvular atrial fibrillation 3.Patients diagnosed with ischemic stroke or transient ischemic attack 4.Patients requiring treatment with apixaban (Elsaban®) for the reduction of the risk of stroke and systemic embolism 5.Patients who voluntarily decide to participate in the study and provide written informed consent
Exclusion criteria
Exclusion criteria: Subjects who meet any of the following criteria will be excluded from the study: 1.Patients with any contraindications listed in the precautions for use of apixaban (Elsaban®) 2.Patients prescribed apixaban (Elsaban®) at a dose not approved according to the product labeling 3.Patients diagnosed with moderate to severe mitral stenosis 4.Patients with a history of mechanical prosthetic heart valve replacement 5.Patients with any of the following laboratory abnormalities: (1) Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) > 2 × upper limit of normal (ULN) (2) Total bilirubin = 1.5 × ULN (3) Creatinine clearance (CrCl) < 15 mL/min 6.Pregnant or breastfeeding women 7.Patients with a history of anaphylaxis or severe hypersensitivity reactions 8.Patients with a history of substance abuse, including alcohol, or psychiatric disorders 9.Patients who have participated in another clinical trial within 90 days prior to screening 10.Patients with a life expectancy of less than 1 year 11.Patients deemed unsuitable for participation in the study by the investigator for any other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of major bleeding | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemorrhagic strok;Ischemic stroke;Systemic embolism;Transient ischemic attack;All-cause mortality;Incidence of AEs and ADRs; incidence of bleeding-related AEs and ADRs | — |
Countries
Korea, Republic of
Contacts
Public ContactNari Hyun
Keimyung University Dongsan Hospital
Outcome results
None listed