Effect of preoperative carbohydrate loading on postoperative neutrophil-to-lymphocyte ratio in patients undergoing spinal cord tumor surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011822

Enrollment

Registered

2026-04-08

Start date

2026-03-20

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : This study is a prospective, randomized controlled trial involving adult patients scheduled to undergo spinal cord tumor surgery at 8:00 AM. After study enrollment and acquisition

16.9 g carbohydrate per 100 mL, 69.29 kcal, osmolarity 273 mOsm/kg). The control group will follow the institution’s standard preoperative fasting guidelines. Thirst will be assessed using a Visual An

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients scheduled to undergo neurosurgical spinal cord tumor surgery at 8:00 AM.

Exclusion criteria

Exclusion criteria: Patients who decline to participate in the study Patients with active infection prior to surgery Patients receiving systemic corticosteroids prior to surgery Patients with a history of preoperative chemotherapy Patients considered to have delayed gastric emptying or an increased risk of aspiration, including: - Patients with uncontrolled diabetes mellitus (HbA1c > 7%) - Patients with symptomatic gastroesophageal reflux disease or esophageal disorders (e.g., dysphagia, frequent nocturnal reflux, ongoing treatment for severe heartburn, esophageal stricture) - Patients with a history of gastric or esophageal surgery - Patients with BMI = 35 kg/m² - Patients with gastrointestinal motility disorders (e.g., gastroparesis, ileus, bowel obstruction) - Patients taking GLP-1 receptor agonists (e.g., exenatide, lixisenatide, liraglutide, dulaglutide, semaglutide, tirzepatide)

Design outcomes

Primary

Measure	Time frame
Neutrophil-to-lymchocyte ratio	—

Secondary

Measure	Time frame
Change in the neutrophil-to-lymphocyte ratio;Preoperative anxiety;Preoperative thirst;Serum glucose level;Postoperative nausea and vomiting and the need for rescue antiemetic medication;Time to first flatus;Time to first ambulation;Quality of Recovery (QOR-15);C-reactive protein;Hospital length of stay;Other postoperative complications	—

Countries

Korea, Republic of

Contacts

Public ContactHyongmin Oh

Seoul National University Hospital

gudals0118@snu.ac.kr+82-2-2072-4908

Outcome results