None listed
Conditions
Interventions
Others(cosmetic) : Participants applied the test cosmetic product twice daily for 12 weeks, immediately after facial cleansing. An appropriate amount (3–4 pumps) was applied evenly to the entire face
Sponsors
Global Medical Research Center
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Females aged 35 to 59 years 2) Subjects who voluntarily signed the informed consent after receiving sufficient explanation of the purpose and procedures of the study 3) Subjects who are able to comply with and complete follow-up visits throughout the study period 4) Healthy subjects without acute or chronic diseases, including any skin diseases
Exclusion criteria
Exclusion criteria: 1) Pregnant or breastfeeding women, or women of childbearing potential who do not agree to use the contraception methods specified in the protocol 2) Presence of lesions at the test site 3) Presence of infectious skin diseases 4) History or presence of allergy or hypersensitivity 5) History of irritation or adverse reactions to cosmetics, pharmaceuticals, or routine sun/UV exposure 6) Receipt of systemic steroid therapy or phototherapy within 1 month prior to study participation 7) Receipt of skin procedures (e.g., scaling/chemical peeling, botulinum toxin injection, filler injection, laser treatment, or tattooing) within 3 months prior to study participation 8) Use of medicinal products with similar functions on the study area within 3 months prior to study initiation 9) Presence of psychiatric disorders, intellectual disabilities, or other mental disorders 10) Any other condition that, in the judgment of the principal investigator or study staff, makes the subject unsuitable for participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Star Zone Wrinkles (Left Periorbital, Right Periorbital, Left Nasolabial Fold, Right Nasolabial Fold, Glabella);Neck Wrinkles;Skin external hydration ;Skin texture ;Epidermal melasma;Dermal melasma;Skin color Index(Tone-up, Radiance, Transparency;Pigmentation within Stratum Corneum;Mid-Face Lifting;Skin internal hydration;Skin barrier;ZIP Water Effects(Skin Moisture Holding Effect);Skin Stratum Corneum | — |
Secondary
| Measure | Time frame |
|---|---|
| survey (star-zone wrinkles (both crow’s feet, both nasolabial folds, and glabellar lines), neck wrinkles, skin surface hydration, skin texture, surface pigmentation, deep melasma, skin tone index (tone-up, radiance, and clarity), spots in the stratum corneum, mid-face lifting, inner skin hydration, skin barrier function, ZIPWater effect (skin moisture holding/locking effect), and improvement of the stratum corneum.) | — |
Countries
Korea, Republic of
Contacts
Public Contacthwiyeong lee
Global Medical Research Center
Outcome results
None listed