None listed
Conditions
Interventions
None listed
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults aged 30 to 60 years. 2. Disease group: Participants with a confirmed diagnosis of at least one of the following conditions: type 2 diabetes mellitus, breast cancer, cardiovascular disease, osteoarthritis, or low back pain. 3. Healthy control group: Participants with no prior diagnosis of type 2 diabetes mellitus, breast cancer, cardiovascular disease, osteoarthritis, or low back pain. 4. No history or current diagnosis of major medical conditions that may affect study outcomes, including but not limited to chronic kidney disease or liver cirrhosis. 5. Ability to understand the study procedures and provision of written informed consent prior to participation.
Exclusion criteria
Exclusion criteria: 1. Participants with incomplete or insufficient clinical or health screening data. 2. Participants considered inappropriate for study participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incident occurrence of each target disease within T years after the index date (binary outcome: yes/no) (Cardiovascular disease, Type 2 diabetes mellitus, Breast cancer, Low back pain, Osteoarthritis) | — |
Secondary
| Measure | Time frame |
|---|---|
| Discriminative performance of the artificial intelligence model in distinguishing between disease and control groups using baseline data from health screenings and clinical records (AUROC, PR-AUC);Diagnostic Performance Metrics (Sensitivity, Specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV)) ;Calibration Performance (Brier score, Calibration slope, Calibration intercept) ;Reclassification Performance Compared With Existing Risk Scores (if applicable) (Net Reclassification Improvement (NRI), Integrated Discrimination Improvement (IDI), if applicable) | — |
Countries
Korea, Republic of
Contacts
Public ContactEUN HA KIM
Asan Medical Center
Outcome results
None listed