None listed
Conditions
Interventions
Behavioral, Others : This study is a non-invasive, behavioral-based clinical study that does not include therapeutic interventions such as medications, medical device treatments, procedures, or surger
Sponsors
Jeonbuk National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Inclusion Criteria for Patients with Myasthenia Gravis (MG) a. Patients diagnosed with myasthenia gravis who meet at least one of the following criteria: i. A significant decremental response on repetitive nerve stimulation testing ii. Positive acetylcholine receptor (AChR) antibody test iii. Positive muscle-specific kinase (MuSK) antibody test iv. Positive response to the neostigmine test v. Clinically significant findings on clinical examination and/or neuroimaging studies b. Individuals who have received an explanation of the purpose and methods of the study and have provided informed consent to participate in the study and examinations c. Adults aged 19 years or older and under 70 years of age (2) Inclusion Criteria for Patients with Cranial Nerve Palsy (CNP) a. Patients diagnosed with cranial nerve palsy who meet at least one of the following criteria: i. Unilateral involvement of the third, fourth, or sixth cranial nerve with definite limitation of extraocular movements ii. Clinically significant findings on clinical examination and/or neuroimaging studies b. Individuals who have received an explanation of the purpose and methods of the study and have provided informed consent to participate in the study and examinations c. Adults aged 19 years or older and under 70 years of age (3) Inclusion Criteria for the Control Group a. Adults aged 19 years or older and under 70 years of age with no neurological abnormalities b. Individuals who have received an explanation of the purpose and procedures of the study and have voluntarily provided written informed consent to participate c. Individuals who are able to cooperate with the administration of video-oculography (VOG) examinations
Exclusion criteria
Exclusion criteria: (1) Exclusion Criteria for Patients with Myasthenia Gravis (MG) a. Individuals under 19 years of age b. Individuals who do not provide informed consent to participate in the study c. Individuals who are unable to cooperate with the study examinations d. Individuals deemed inappropriate for study participation at the discretion of the investigator (2) Exclusion Criteria for Patients with Cranial Nerve Palsy (CNP) a. Individuals under 19 years of age b. Individuals who do not provide informed consent to participate in the study c. Individuals who are unable to cooperate with the study examinations d. Individuals deemed inappropriate for study participation at the discretion of the investigator (3) Exclusion Criteria for the Control Group a. Individuals under 19 years of age or over 70 years of age b. Individuals who do not provide informed consent to participate in the study c. Individuals who are unable to cooperate with the study examinations d. Individuals deemed inappropriate for study participation at the discretion of the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Video-Oculography | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Ab level;Repetitive Nerve Stimulation Test;Tensilon Test;Ice Cube Test;Brain MRI;MG-ADL Score | — |
Countries
Korea, Republic of
Contacts
Public ContactSunyoung Oh
Jeonbuk National University Hospital
Outcome results
None listed