Effect of remimazolam versus propofol total intravenous anesthesia on postoperative nausea and vomiting in patients undergoing microvascular decompression

Effect of remimazolam versus propofol total intravenous anesthesia on postoperative nausea and vomiting in patients undergoing microvascular decompression: a double-blind randomized study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011740

Enrollment

Registered

2026-03-18

Start date

2026-03-23

Completion date

Unknown

Last updated

2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Upon arrival in the operating room, standard anesthesia monitoring will be applied, including electrocardiography (ECG), non-invasive blood pressure (NIBP), pulse oximetry, capnography, and bi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 20 to 75 years with trigeminal neuralgia or hemifacial spasm who are scheduled to undergo elective microvascular decompression under general anesthesia, and who are classified as American Society of Anesthesiologists (ASA) physical status I–III.

Exclusion criteria

Exclusion criteria: (1) Patients with known allergy or contraindication to the study drugs (2) Patients with obesity defined as a body mass index (BMI) = 35 kg/m² (3) Patients who have received antiemetic medication prior to surgery (4) Patients with chronic use of benzodiazepines or opioids (5) Patients with hepatic failure (6) Patients who do not provide consent for study participation

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative nausea and vomiting	—

Secondary

Measure	Time frame
quality of recovery assessed using the QoR-15K questionnaire;intraoperative opioid requirement	—

Countries

Korea, Republic of

Contacts

Public ContactANN HEE YOU

Kyung Hee University

ahyou@khu.ac.kr+82-2-958-8581

Outcome results