None listed
Conditions
Interventions
None listed
Sponsors
Chonnam National University Hwasun Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with colon or rectal cancer at Chonnam National University Hwasun Hospital. 2. Patients scheduled to undergo curative surgery for colon cancer or neoadjuvant chemoradiotherapy (CRT) or total neoadjuvant therapy (TNT) followed by surgery for rectal cancer. 3. Adults aged 20 years or older. 4. Patients who provide written informed consent to participate in the study. 5. Patients from whom fecal and blood samples can be collected for microbiome and biomarker analyses.
Exclusion criteria
Exclusion criteria: 1. Patients who do not provide informed consent for study participation. 2. Patients with inflammatory bowel disease (IBD) or hereditary colorectal cancer syndromes (e.g., familial adenomatous polyposis, Lynch syndrome). 3. Patients who have used systemic antibiotics, probiotics, or immunosuppressive agents within 4 weeks prior to enrollment, which may significantly alter gut microbiota composition. 4. Patients for whom fecal or blood sample collection is not feasible. 5. Patients who are considered unsuitable for participation by the investigators due to medical or clinical reasons that may interfere with study outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative complications occurring within 30 days (Clavien–Dindo grade II or higher) | — |
Secondary
| Measure | Time frame |
|---|---|
| Response to neoadjuvant therapy | — |
Countries
Korea, Republic of
Contacts
Public ContactSoo Young Lee
Chonnam National University Hwasun Hospital
Outcome results
None listed