None listed
Conditions
Interventions
Others(Functional cosmetics) : The test products are CosmeRNA-DKK1 (low concentration) and CosmeRNA-DKK1 (high concentration). Apply an appropriate amount of the test or reference product evenly to dr
Sponsors
Bioneer
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Male or female applicants diagnosed with androgenetic alopecia (based on the MFDS Guideline) aged 18 to 54 years (1) Applicants diagnosed with androgenetic alopecia diagnosed with M1, C1, or U1 or higher for basic type and V1 or F1 or higher for specific type according to the Basic and Specific (BASP) classification (2) Male applicants diagnosed with 2 or 2A or higher for androgenetic alopecia according to the Norwood-Hamilton classification (3) Female applicants diagnosed with 1 or higher for androgenetic alopecia according to the Ludwig classification ? Applicants who will not use any special hair products or hair care or manipulation (dyeing, perming, etc.) during the study period ? Applicants who will maintain the same hair style and color as at the first visit during the study period ? Applicants who have received a sufficient explanation of the purpose and content of the study from the researcher and voluntarily completed and signed a consent form for clinical research participation ? Applicants who are available for follow-up observation during the study period
Exclusion criteria
Exclusion criteria: ? Applicants who have suffered from serious acute kidney or heart disease or other chronic diseases (e.g., hypertension, diabetes) that may affect test results within the past 6 months. ? Applicants who are pregnant, breastfeeding, or planning to become pregnant within the next 6 months. ? Applicants with psychiatric disorders or infectious skin diseases. ? Applicants who have undergone surgical procedures for hair loss, such as hair transplantation or scalp reduction surgery. ? Applicants who have taken oral Dutasteride or Finasteride within the past 6 months. ? Applicants who have applied topical hair growth agents, hair growth agents, or hair tonics within the past month. ? Applicants who have taken the following medications within the past month: steroids, apoptotic agents, vasodilators, antihypertensives, antiepileptics, beta-blockers, bronchodilators, diuretics, spironolactone, cimetidine, diazoxide, cyclosporine, ketoconazole. ? Applicants who have applied topical steroid preparations to the scalp within the past month. ? Severe seborrheic dermatitis, Applicants who are judged to have difficulty applying the test substance due to scalp psoriasis, scalp infection, etc. ? Applicants with other hair loss diseases such as alopecia areata, telogen effluvium, and cicatricial alopecia in addition to androgenetic alopecia ? Applicants who are malnourished due to excessive dietary restrictions or gastrectomy, or who are taking nutritional supplements that may affect hair loss ? Applicants who have participated in the same test less than 3 months ago ? Applicants who are employees of this clinical research institute ? Applicants who are judged to be unsuitable for this study by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hair count assessment;Expert visual evaluation | — |
Secondary
| Measure | Time frame |
|---|---|
| Dickkopf-1 expression level;Cortisol in saliva;Hair thickness;Perceived Stress Scale;Efficacy questionnaire evaluation | — |
Countries
Korea, Republic of
Contacts
Public ContactDasom Jeon
Korea Biomedical Research Institute
Outcome results
None listed