None listed
Conditions
Interventions
Drug : This study is a randomized, double-blind, multicenter, parallel-group clinical trial comparing two opioid-based analgesic strategies in adult patients requiring mechanical ventilation in surgic
Sponsors
Keimyung University Dongsan Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients aged 18 years or older Patients admitted to a surgical intensive care unit requiring mechanical ventilation Patients requiring opioid-based analgesia for sedation management Written informed consent obtained from the patient or a legally authorized representative
Exclusion criteria
Exclusion criteria: Known hypersensitivity or contraindication to sufentanil or fentanyl Severe neurologic conditions precluding reliable delirium assessment (e.g., persistent coma, severe brain injury) Presence of delirium at baseline prior to randomization Pregnancy or breastfeeding Any condition judged by the investigator to make participation inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delirium during ICU stay. Delirium is assessed using the Confusion Assessment Method for the ICU (CAM-ICU). Delirium occurrence is defined as at least one positive CAM-ICU assessment during the ICU stay. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of delirium during ICU stay, defined as the total number of days with a positive CAM-ICU assessment. | — |
Countries
Korea, Republic of
Contacts
Public ContactChanhee Park
Keimyung University Dongsan Hospital
Outcome results
None listed