None listed
Conditions
Interventions
Others(Acupuncture treatment, Herbal mouthwash) : 1) Acupuncture Group
Intervention: Electroacupuncture treatment
Acupoints: ST7 (Xiaguan), ST6 (Jiache), LI4 (Hegu), with optional additional acupoints
gargle for approximately 30 seconds and then spit out
Treatment period: 4 weeks
3) Control Group
Intervention: Oral hygiene education and standard self-care management
Sponsors
Dongguk University Ilsan Oriental Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Male and female participants aged 20 years or older and under 65 years. (2) Individuals diagnosed with gingivitis or mild periodontitis. (3) Individuals who have voluntarily provided written informed consent to participate in this study.
Exclusion criteria
Exclusion criteria: (1) Patients with severe or advanced periodontitis. (2) Individuals who have received scaling or preventive periodontal treatment within 3 months prior to the date of informed consent. (3) Current smokers. (4) Individuals wearing orthodontic appliances. (5) Individuals with pathological lesions of the oral soft tissues requiring evaluation or treatment by other medical or dental specialties. (6) Individuals who require immediate treatment for dental caries. (7) Individuals with uncontrolled chronic diseases, including diabetes mellitus, liver disease, cardiovascular disease, renal disease, or bleeding disorders. (8) Individuals requiring treatment for clinically significant immune disorders, infectious diseases, malignancies, or psychiatric disorders. (9) Individuals currently taking medications known to affect periodontal disease, such as nifedipine, phenytoin, or cyclosporine. (10) Individuals who have taken antibiotics within the past 4 weeks, are currently taking antibiotics, or are scheduled to receive antibiotic therapy during the study period. (11) Individuals who have received investigational drugs or investigational medical devices within 30 days prior to study participation. (12) Pregnant or breastfeeding women, or women of childbearing potential who are not using an acceptable method of contraception. (13) Individuals who are deemed inappropriate for participation in the study by the principal investigator or study staff for any other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Study feasibility test | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing Depth, Bleeding on Probing, Gingival index, Plaque index;Visual analog scale;Salivary biomarkers (IL-1ß, IL-6, TNF-a, MMPs, and TIMP-1);Quality of Life Questionnaire (EQ-5D-5L);Subgingival microbiome | — |
Countries
Korea, Republic of
Contacts
Public ContactKyungsun Han
Dongguk University Ilsan Oriental Hospital
Outcome results
None listed