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Long-term Effects of Oral-Gut Microbiome and Lifestyle Factors on Disease Incidence: Korean Cohort Study

Long-term Effects of Oral-Gut Microbiome and Lifestyle Factors on Disease Incidence: Korean Cohort Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0011594
Enrollment
200
Registered
2026-02-10
Start date
2025-10-10
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Apple Tree Medical Foundation
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Adults aged 19 years and older (2) Individuals who voluntarily agreed to participate after receiving explanation of the study purpose and methods

Exclusion criteria

Exclusion criteria: (1) Individuals who have used antibiotics (oral or injection) within the past week (2) Individuals deemed unsuitable for study participation by the principal investigator based on clinical judgment

Design outcomes

Primary

MeasureTime frame
Changes in oral and gut microbiome composition (Oral: P. gingivalis, T. denticola, T. forsythia, P. intermedia, C. rectus, F. nucleatum, S. mutans; Gut: 16S rRNA metagenomic analysis);Changes in metabolic, inflammatory, hematological parameters and anthropometric measurements;Disease incidence (periodontal disease, metabolic diseases, cognitive decline)—

Secondary

MeasureTime frame
Changes in lifestyle factors (alcohol consumption, smoking, dietary habits, exercise habits, bowel movements);Changes in anthropometric measurements and vital signs (height, weight, BMI, blood pressure, pulse)—

Countries

Korea, Republic of

Contacts

Public ContactMu-Yeol Cho

Apple Tree Medical Foundation

whanduf@appleden.com+82-2-4601-5479

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Mar 14, 2026