None listed
Conditions
Interventions
None listed
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 19 or older 2. Requires mitral valve replacement due to mitral valve dysfunction 3. The participant or their guardian can provide a written consent form approved by the IRB and agree to the research protocol and clinical follow-up schedule.
Exclusion criteria
Exclusion criteria: 1. Life expectancy of less than one year due to causes other than cardiovascular disease 2. High-risk candidates for mitral valve replacement: Society of Thoracic Surgeons Predicted Risk of Mortality 10% or greater; EuroSCORE 10% or greater; estimated surgical mortality rate by the surgeon 10% or greater 3. Chronic kidney disease: eGFR <30 mL/min/1.73m² 4. Undergoing surgery for infective endocarditis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiovascular death ;Valve-related intervention ;Structural valve deterioration and non-structural valve dysfunction | — |
Secondary
| Measure | Time frame |
|---|---|
| structural valve deterioration or non-structural valve dysfunction;valve thrombosis;Peak and mean trans-mitral valve pressure gradient and effective orifice area ;All-cause death ;cardiovascular death;Valve-related death;ischemic or hemorrhagic stroke;Hospitalization due to causes related to cardiovascular disease;Bleeding ;Infective endocarditis of the mitral valve;valve-related reintervention | — |
Countries
Korea, Republic of
Contacts
Public ContactHONGBI LEE
Asan Medical Center
Outcome results
None listed