Effects of Hyperbaric Oxygen Therapy on Microbiome Recovery in Subacute Burn Patients: Therapeutic Outcomes and Clinical Applicability

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011539

Enrollment

Registered

2026-01-26

Start date

2025-12-27

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : Intervention (HBOT group): Participants in the intervention group will receive hyperbaric oxygen therapy (HBOT) in a medical-grade hyperbaric chamber under a pressure of 2.0 atmospher

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Adult burn patients aged 19 to ~ 64 years -Burn wounds completely healed (complete epithelialization) after conservative wound care and/or skin grafting -Able to comply with the study schedule (HBOT sessions and three assessment visits) and able to provide written informed consent

Exclusion criteria

Exclusion criteria: -Use of systemic antibiotics or systemic steroids (oral or injectable) within the past 2 weeks -Pregnant or breastfeeding women -Conditions that may substantially affect the microbiome or skin characteristics (e.g., diabetes mellitus or chronic skin diseases), as judged by the principal investigator -Contraindications to HBOT (e.g., untreated pneumothorax) or any medical condition deemed inappropriate for HBOT by the principal investigator -Considered unable to comply with study participation or follow-up (e.g., inability to adhere to the schedule)

Design outcomes

Primary

Measure	Time frame
Skin microbiome (burn scar and matched non-burned skin)	—

Secondary

Measure	Time frame
Blood inflammatory markers	—

Countries

Korea, Republic of

Contacts

Public ContactYeonGyun Jung

Hallym University Medical Center-Hangang

jyg1076@gmail.com+82-2-2639-5730

Outcome results