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The Effects of Hyperbaric Oxygen Therapy on the Skin Microbial Dysbiosis of Burn Patients: A Retrospective Cohort Study

The Effects of Hyperbaric Oxygen Therapy on the Skin Microbial Dysbiosis of Burn Patients: A Retrospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0011500
Enrollment
112
Registered
2026-01-20
Start date
2025-12-26
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Hallym University Medical Center-Hangang
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: -Patients who were hospitalized and treated for burn injuries at Hallym University Hangang Sacred Heart Hospital -Patients with subacute burn injuries who achieved complete wound re-epithelialization through sterile wound care or skin graft surgery -Adult patients aged 19 to 65 years at the time of evaluation -Patients who participated in a previous microbiome study and had available skin microbiome data from burn scar sites -Patients with accessible clinical and skin assessment data through medical record review

Exclusion criteria

Exclusion criteria: -Patients with a history of systemic or topical antibiotic or steroid use within two weeks prior to evaluation -Patients with chronic skin diseases that may affect the skin microbiome (e.g., atopic dermatitis, psoriasis) -Patients with severe systemic diseases, including diabetes mellitus, heart failure, chronic kidney disease, liver cirrhosis, or chronic lung disease -Patients with contraindications to hyperbaric oxygen therapy, such as pneumothorax, emphysema, sinusitis, otitis media, alveolar injury, acute respiratory infection, or obstructive pulmonary disease -Patients diagnosed with electrical burns -Patients deemed inappropriate for study inclusion based on the investigator’s judgment

Design outcomes

Primary

MeasureTime frame
Skin microbiome parameters at burn scar sites

Secondary

MeasureTime frame
Skin biomechanical properties

Countries

Korea, Republic of

Contacts

Public ContactYeonGyun Jung

Hallym University Medical Center-Hangang

jyg1076@gmail.com+82-2-2639-5730

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026