The Impact of Pelubi on Postoperative Pain and Range of Motion Recovery After Total Knee Arthroplasty: Comparison with Celebrex

Short-Term Effects of Perioperative Administration of Celecoxib and Pelubiprofen on Pain, and Range of Motion After Total Knee Arthroplasty: A Preliminary Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011481

Enrollment

100

Registered

2026-01-16

Start date

2024-05-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : All patients received an identical postoperative analgesic protocol after total knee arthroplasty, including Tylenol® 8-hour extended-release (three times daily), Ultracet® 325/37.5 mg (twice d

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent total knee arthroplasty for knee osteoarthritis at our institution during the two-year period following Institutional Review Board (IRB) approval.

Exclusion criteria

Exclusion criteria: Patients with an American Society of Anesthesiologists (ASA) physical status classification of grade III or higher. Patients with a history of previous surgery on the affected knee. Patients with known hypersensitivity, allergy, or contraindications to any of the medications used for pain control in this study, or those who do not consent to their use. Patients who are continuously using analgesic medications for reasons unrelated to the present study. Patients with significant cardiovascular disease, renal disease, or hematologic disorders. Patients with severe obesity, defined as a body mass index (BMI) greater than 35 kg/m².

Design outcomes

Primary

Measure	Time frame
Postoperative pain intensity measured using a 100-mm visual analog scale (VAS)	—

Secondary

Measure	Time frame
Postoperative pain intensity measured using a 100-mm visual analog scale (VAS);Knee range of motion (ROM);Patient satisfaction score;Total amount of additional analgesic consumption	—

Countries

Korea, Republic of

Contacts

Public ContactYong Beom Park

Chung-Ang University Gwangmyeong Hospital

whybe1122@gmail.com+82-2-2610-6651

Outcome results