The Effect of Coagulation Factor Concentrate Use in Non-Cardiac Surgery on Intraoperative Coagulation Function and Treatment of Coagulopathy

The Effect of Coagulation Factor Concentrates (PPC or FC) Use in Non-Cardiac Surgery on Intraoperative Coagulation Function and Treatment of Coagulopathy: A Multicenter Comparative Study Against Fresh Frozen Plasma or Cryoprecipitate Use

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0011445

Enrollment

Registered

2026-01-12

Start date

2026-01-31

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : When bleeding occurs during surgery, perform a TEG6 test immediately afterward if bleeding exceeds 500ml or if coagulation dysfunction is suspected in the surgical field. If coagulation dysfunc

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: * ASA physical status 1-3 * Age: 19 years or older * Individuals scheduled for non-cardiac surgery with a high risk of bleeding * Spinal surgery (2 levels or more), joint replacement, radical prostatectomy, hepatectomy * Individuals who have signed the study participation consent form

Exclusion criteria

Exclusion criteria: * Refusal of informed consent * Pregnancy * Patients aged 80 years or older * Patients refusing blood transfusions * Patients with concomitant coagulation disorders * Patients receiving recombinant factor VIIa * Patients who verbally or in writing withdraw consent after initial agreement * Other patients deemed unsuitable for the study by the research team

Design outcomes

Primary

Measure	Time frame
Time required for coagulation disorder treatment	—

Secondary

Measure	Time frame
Time of completion for administration of other blood products (packed red blood cells, cryoprecipitate, platelets)	—

Countries

Korea, Republic of

Contacts

Public ContactInchul Choi

Asan Medical Center

icchoi@amc.seoul.kr+82-2-3010-3862

Outcome results