None listed
Conditions
Interventions
Medical Device : The intervention in this study is a non-invasive electrical stimulation therapy using galvanic vestibular stimulation (GVS)-based transcranial direct current stimulation, conducted to
Sponsors
Jeonbuk National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Age: Individuals aged 50 to 80 years ? Ability to understand the study and communicate: Individuals who are able to understand the study objectives and procedures, follow the instructions provided by the investigator, and communicate effectively ? Informed consent: Individuals who voluntarily agree to participate in the study and to undergo follow-up assessments, with written informed consent obtained ? Diagnostic criteria: -Mild Cognitive Impairment (MCI) group Individuals who report subjective memory decline (reported by the participant or a caregiver) Korean version of the Mini-Mental State Examination score between 20 and 27 Clinical Dementia Rating score of 0.5 Preserved activities of daily living within the normal range -Dementia group Korean version of the Mini-Mental State Examination score of 19 or below Clinical Dementia Rating score of 1 or higher Confirmed impairment in activities of daily living ? Investigator’s judgment: Individuals deemed appropriate for participation in the study by the investigator
Exclusion criteria
Exclusion criteria: Participants will be excluded from the study if they meet one or more of the following criteria: ? Presence of major psychiatric disorders (e.g., major depressive disorder, schizophrenia). ?History of neurological diseases such as stroke, brain tumor, or severe traumatic brain injury. ?History of active epilepsy or other seizure disorders. ?Implantation of electronic medical devices such as a pacemaker or implantable cardioverter-defibrillator. ?Severe visual or auditory impairment that makes cognitive assessment impossible. ?Determined by the investigator to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Object and Space Perception Battery, ;Corsi Block Tapping Test; Virtual Morris Water Maze | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in overall cognitive function, ;changes in vestibular and oculomotor function;changes in brain functional connectivity (based on fMRI) | — |
Countries
Korea, Republic of
Contacts
Public ContactSunyoung Oh
Jeonbuk National University
Outcome results
None listed