Comparison of probiotics with traditional dietary advice and traditional dietary advice for non-constipated irritable bowel syndrome patients

Comparison of probiotics with traditional dietary advice and traditional dietary advice for non-constipated irritable bowel syndrome patients: A open-label, prospective, randomized controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011321

Enrollment

112

Registered

2025-12-15

Start date

2025-05-14

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : Probiotics and Traditional Dietary Therapy for Irritable Bowel Syndrome Food for Human Application Trial Enterococcus species, Bacillus subtilis, and Lactobacillus casei (3 Formu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Adult men and women 19 years of age or older 2) Signed written informed consent after receiving an explanation of the purpose and methods of the study 3) Irritable bowel syndrome according to Rome IV criteria

Exclusion criteria

Exclusion criteria: 1) Under the age of 19 2) Subjects who do not consent to participate in the study 3) Past history of abdominal surgery (except appendectomy, cesarean section) 4) Patients with inflammatory bowel disease, major psychiatric disorders and those taking medication for depression 5) Subjects with severe cardiopulmonary disease and malignant tumors 6) Taking antibiotics or probiotics or undergoing a fecal transplant within 2 weeks of study enrollment

Design outcomes

Primary

Measure	Time frame
Change of IBS Symptom Severity assessed with the IBS Severity Scoring System (50 points or more decrease)	—

Secondary

Measure	Time frame
Change of abdominal pain Severity assessed with the IBS Severity scoring System (10 points or more decrease);Change of Irritable Bowel Syndrome Quality of Life Score (10 points or more decrease)	—

Countries

Korea, Republic of

Contacts

Public ContactChang Kyo Oh

Hallym University Medical Center-Kangnam

ckdryekd@gmail.com+82-2-829-5210

Outcome results