None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Subjects who have received consent ? Adults aged 19 years or older ? Subjects who have visited the emergency room ? Patients diagnosed with acute CO poisoning
Exclusion criteria
Exclusion criteria: ? Patients who did not consent to the study ? Patients under 19 years of age ? Pregnant women ? Inmates and institutionalized persons ? Employees of research institutions, researchers, sponsors, etc. ? Patients with persistent neurological complications (PNS) due to severe CO intoxication ? Cardiac arrest prior to hyperbaric oxygen therapy ? History of neurological disease ? Patients with a critical medical history (e.g., terminal cancer) ? Patients who were transferred from the study midway through participation ? Patients who are unable to undergo MRI due to implantation of a pacemaker or cochlear implant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurological status assessment: Geriatric Depression Scale (GDS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological status assessment: Mini-Mental Status Exam (MMSE, Korean version), Korean Modified Barthel Index (KMBI);Neurological status assessment: Geriatric Depression Scale (GDS), Mini-Mental Status Exam (MMSE, Korean version), Korean Modified Barthel Index (KMBI);Hematological status assessment: Serum Myelin Basic Protein (MBP), Serum Neuron-Specific Enolase (NSE), Serum S-100 protein;Hematological status assessment: Serum Myelin Basic Protein (MBP), Serum Neuron-Specific Enolase (NSE), Serum S-100 protein | — |
Countries
Korea, Republic of
Contacts
Yonsei University Wonju College of Medicine