Skip to content

Uncovering Brain Changes After Carbon Monoxide Poisoning: Insights from MRI and Blood Tests

Exploring Ferroptosis in Delayed Neurological Sequelae of Acute Carbon Monoxide Poisoning through MRI Findings and Biomarker Assessment: A Prospective Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0011258
Enrollment
49
Registered
2025-12-05
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Yonsei University, Wonju Severance Christian Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? Subjects who have received consent ? Adults aged 19 years or older ? Subjects who have visited the emergency room ? Patients diagnosed with acute CO poisoning

Exclusion criteria

Exclusion criteria: ? Patients who did not consent to the study ? Patients under 19 years of age ? Pregnant women ? Inmates and institutionalized persons ? Employees of research institutions, researchers, sponsors, etc. ? Patients with persistent neurological complications (PNS) due to severe CO intoxication ? Cardiac arrest prior to hyperbaric oxygen therapy ? History of neurological disease ? Patients with a critical medical history (e.g., terminal cancer) ? Patients who were transferred from the study midway through participation ? Patients who are unable to undergo MRI due to implantation of a pacemaker or cochlear implant

Design outcomes

Primary

MeasureTime frame
Neurological status assessment: Geriatric Depression Scale (GDS)

Secondary

MeasureTime frame
Neurological status assessment: Mini-Mental Status Exam (MMSE, Korean version), Korean Modified Barthel Index (KMBI);Neurological status assessment: Geriatric Depression Scale (GDS), Mini-Mental Status Exam (MMSE, Korean version), Korean Modified Barthel Index (KMBI);Hematological status assessment: Serum Myelin Basic Protein (MBP), Serum Neuron-Specific Enolase (NSE), Serum S-100 protein;Hematological status assessment: Serum Myelin Basic Protein (MBP), Serum Neuron-Specific Enolase (NSE), Serum S-100 protein

Countries

Korea, Republic of

Contacts

Public ContactHee Young Lee

Yonsei University Wonju College of Medicine

hylee3971@yonsei.ac.kr+82-33-741-0952

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026