Long-term effect of Home Meal Replacement (HMR) containing eggshell and vitamin D and exercise on the preventive effect of bone loss in postmenopausal women

Long-term effect of age-friendly Home Meal Replacement (HMR) containing eggshell and vitamin D and exercise on the preventive effect of bone loss in postmenopausal women

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011253

Enrollment

Registered

2025-12-04

Start date

2023-10-20

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(Eggshell Calcium and Vitamin D–Fortified Home Meal Replacement) : The Home Meal Replacement is consumed as a snack five times a week. It is designed so that the product differences between the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? Postmenopausal women aged 50 to 60 years who meet at least one of the following conditions: a. Spontaneous amenorrhea lasting for 12 months b. Last menstruation occurred 6 months to less than 1 year ago with blood FSH > 40 mIU/mL ? Body Mass Index (BMI) between 18.5 and 30.0 kg/m² ? Provided informed consent voluntarily after receiving sufficient explanation about this clinical trial before starting the study

Exclusion criteria

Exclusion criteria: ? Osteoporosis (T-score 10 uIU/ml or 10.2 mg/dL). However, if the investigator judges that hypercalcemia or hypocalcemia is a temporary condition (for example, ionized calcium levels are normal, or the subject is asymptomatic and has undergone bowel preparation for screening, or has muscle soreness from intense exercise, or has bruises or other temporary physical injuries), the subject may still be eligible for enrollment. ? Uncontrolled chronic diseases affecting bone metabolism (e.g., chronic liver disease, alcoholism, primary hyperparathyroidism), metabolic bone diseases other than osteopenia, ongoing medications affecting bone/calcium metabolism (e.g., steroids, diuretics except those in antihypertensives), clinically significant allergies including investigational food components (e.g., eggshell or egg allergy) ? Participation in other clinical trials within 1 month before this study or planned participation during the study period ? Individuals deemed unsuitable by the investigator (e.g., frequent relocations or travel interfering with study participation)

Design outcomes

Primary

Measure	Time frame
Bone mineral density assessed by dual-energy X-ray absorptiometry at the spine and femur	—

Secondary

Measure	Time frame
Bone turnover markers(urine N-telopeptide, serum osteocalcin, serum 25-hydroxyvitamin D, serum calcium, urine calcium to creatinine ratio)	—

Countries

Korea, Republic of

Contacts

Public ContactSusie Jung

Ajou University Hospital

lovehrh@naver.com+82-31-219-5219

Outcome results