None listed
Conditions
Interventions
None listed
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Acute hemorrhagic stroke patients including subarachnoid hemorrhage (SAH) d/t aneurysm rupture, arterio-venous malformation (AVM) or cavernous malformation (CM) rupture, (hypertensive) intracranial or intraventricular hemorrhage (ICH or IVH) 2. Acute traumatic brain injury [epidural hematoma (EDH), subdural hematoma (SDH), subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), intraventricular hemorrhage (IVH), diffuse axonal injury, concussion]
Exclusion criteria
Exclusion criteria: 1. Experience infection within recent 1 month 2. Concomitant medical illness that may interfere with the study outcome assessments and/or follow up 2.1 Systemic malignant tumor (brain, lung, gastric, colon, liver, breast and etc.) 2.2 Any autoimmune disease 2.3 Steroids medication history 3. History of neurological disease (stroke, head trauma etc.), causing significant cognitive and/or motor strength deficit 4. Pregnancy 5. GCS < 6; brain death or imminent death (within 72 hours) 6. DNR (do not resuscitate) ordered patient 7. Currently participating in other investigational trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of infections occurred during hospitalization after cerebral hemorrhage | — |
Secondary
| Measure | Time frame |
|---|---|
| Glasgow Coma Scale;modified Rankin Scale;Inflammation-related biomarkers concentration;Mechenical ventilation period;Intensive care unit stay and hospitalization periods | — |
Countries
Korea, Republic of
Contacts
Public ContactHyunchul Jung
Asan Medical Center
Outcome results
None listed