None listed
Conditions
Interventions
Others : Apply this product once daily after cleansing, gently spreading it on before bedtime.
Sponsors
Dermacle, Inc.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female aged between 40 and 70 years 2. Individuals experiencing insomnia due to aging or menopausal symptoms 3. Individuals meeting or exceeding the criteria after PSQI-K [Pittsburgh Sleep Quality Index-Korean] questionnaire assessment 4. Individuals with wrinkles around the eyes 5. Individuals with dark circles caused by vascular or pigmentary factors 6. Individuals who have fully understood the objective and have voluntarily filled out and signed a consent form after receiving sufficient explanation about the information that should be provided to the subjects by the principal investigator or their delegate 7. Healthy individuals without acute or chronic physical diseases, including skin diseases 8. Individuals who can be monitored during the study period
Exclusion criteria
Exclusion criteria: 1. Female who are pregnant, breast feeding or planning pregnancy 2. Individuals with abnormal skin findings at the test site 3. Individuals who have infectious skin diseases 4. Individuals with significant nutritional disorders 5. Individuals with drug or alcohol addiction 6. Individuals with sagging under the eyes that may be mistaken for dark circles 7. Individuals who have allergies or hypersensitive skin 8. Individuals who are sensitive to cosmetics, medications, or normal light exposure 9. Individuals who have received systemic steroids or phototherapy within 1 month of participating in the study 10. Individuals who have received skin care or procedures (scaling, Botox, fillers, laser treatments, tattoos) within 3 months of participating in the study 11. Individuals with mental illness or intellectual disabilities. 12. Individuals who have used topical steroid-containing skin preparations for more than 1 month for the treatment of skin diseases 13. Individuals who have not passed 3 months after participating in the same study 14. Other individuals who are considered unsuitable for the study by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Crow's feet;Skin elasticity;Skin Lifting (Angle);Skin density;Skin water loss;Dark circles(grade, brightness, melanin);Skin Volume;Skin elasticity recovery;Skin texture (roughness);Skin radiance;Skin tone;Sleep time;Sleep Questionnaire (PSQI-K);PHQ-9 Questionnaire;Identification of neuro-inflammation factors through tape stripping methodology;Detection of cortisol, melatonin, oxytocin and substanceP secreted in saliva | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse reactions | — |
Countries
Korea, Republic of
Contacts
Public ContactJeong YunJi
Dermacle, Inc.
Outcome results
None listed