None listed
Conditions
Interventions
Procedure/Surgery : [Ultrasound-Guided Pharmacopuncture]
- The type of pharmacopuncture solution and injection site are determined based on the practitioner’s evaluation, including the Four Diagnostic
Sponsors
Pusan National University Korean Medicine Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Patients experiencing hand numbness and pain for at least 3 months, with a VAS score = 50 mm on a 100-mm scale. ? Male or female adults aged 19 to 70 years. ? Patients who meet at least one of the following criteria (for bilateral cases, the side with more severe symptoms is evaluated): ? Presence of sensory abnormalities (e.g., hypoesthesia) in the median nerve distribution (palmar aspect of the thumb, index, middle, and radial half of the ring finger; dorsal aspect of the distal phalanges of the index, middle, and radial half of the ring finger). ? Thenar muscle atrophy compared with the contralateral side. ? Positive result on at least one of the following: Phalen test or Tinel sign. ? Able to communicate normally. ? Patients who voluntarily agree to clinical participation and follow-up, and who provide written informed consent approved by the Institutional Review Board (IRB).
Exclusion criteria
Exclusion criteria: ? Patients with neurological symptoms of the hand caused by conditions other than carpal tunnel syndrome, such as polyneuropathy, brachial plexopathy, thoracic outlet syndrome, or cervical disc herniation. ? Patients reporting hand sensory abnormalities due to systemic diseases such as rheumatoid arthritis, diabetes mellitus, thyroid disorders, or hormonal imbalance. ? Patients who have undergone surgery on the wrist or have received steroid injections or other medical injection treatments (e.g., local anesthetic injections) in the wrist within 1 month prior to screening. ? Patients who have received Korean medicine treatments (e.g., acupuncture, pharmacopuncture, moxibustion, cupping) on the wrist within 2 weeks prior to screening. However, if the treatment was administered at another institution for a reason unrelated to the condition targeted by this clinical trial, participation may be allowed at the investigator’s discretion. ? Patients who have taken systemic steroids, antipsychotics, antidepressants, anticonvulsants, or anxiolytics/sedatives within 1 month prior to screening, or other medications affecting pain (e.g., NSAIDs) that may influence the study results. Patients taking anxiolytics/sedatives at a stable dose for at least 4 weeks prior to screening are not excluded. ? Pregnant women or women who may be pregnant. ? Patients with serious systemic infections or other internal medical conditions considered inappropriate for study participation. ? Patients with wrist fractures, trauma, congenital deformities, or implanted devices in the wrist area. ? Patients for whom pharmacopuncture is considered inappropriate or unsafe (e.g., bleeding disorders, severe diabetes with high infection risk). ? Patients who have participated in another clinical study within the past month, or who plan to participate in another clinical study during this trial and its follow-up period. ? Patients unable to provide written informed consent. ? Any other individuals deemed unsuitable for participation at the investigator’s discretion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hand numbness and pain Visual Analogue Scale, VAS | — |
Secondary
| Measure | Time frame |
|---|---|
| Boston carpal tunnel questionnaire, BCTQ;cross-sectional area, CSA;grip strength;Adverse events | — |
Countries
Korea, Republic of
Contacts
Public ContactLEE JUNG-GYUNG
Pusan National University Korean Medicine Hospital
Outcome results
None listed