None listed
Conditions
Interventions
None listed
Sponsors
Kyung Hee University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy young adults aged 20-29 years and healthy elderly individuals aged =70 years
Exclusion criteria
Exclusion criteria: Abnormal BMI History of physician-diagnosed cardiovascular disease (excluding controlled hypertension), diabetes, autoimmune disease, respiratory disease, kidney disease, blood-borne infections, endocrine disorders, or gastrointestinal disorders History of physician-diagnosed neurodegenerative diseases (dementia, Alzheimer's disease, Parkinson's disease) or psychiatric disorders (depression, schizophrenia, bipolar disorder) Cognitive impairment indicated by K-MMSE score 1 beer or >2 shots of soju per occasion, =5 days/week) Current smoking or recent smoking cessation (<6 months)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene expression patterns of immune cell subsets associated with inflammaging through single-cell RNA sequencing analysis; Taxonomic composition and functional gene profiles of gut microbiota through metagenomic analysis;Expression levels and concentrations of multiple protein biomarkers in serum through SomaScan analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Lifestyle and mental health indicators | — |
Countries
Korea, Republic of
Contacts
Public ContactMinju Sim
Kyung Hee University
Outcome results
None listed