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Changes in Inflammatory Markers and Physical Fitness Following Modulation of Exercise Intensity and Volume in Women with Sarcopenic Obesity

Effects of the Intensity and Volume of Aerobic and Resistance Exercise on Inflammatory Markers and Functional Fitness in Sarcopenic Obese Older Women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0011123
Enrollment
100
Registered
2025-11-10
Start date
2017-06-30
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(exercise intervention) : The aerobic exercise program in this study was conducted on a treadmill and targeted elderly women with sarcopenic obesity. The exercise intensity was set at a low leve

Sponsors

Pusan National University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: In the initial screening for sarcopenic obesity, sarcopenia had been assessed according to the diagnostic criteria outlined in the Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. The criteria had included: calf circumference < 33 cm, handgrip strength < 18 kg, gait speed < 1.0 m/s during a 6-meter walk, time = 12 seconds to complete five repeated chair stands, and a total score = 9 on the Short Physical Performance Battery (SPPB). Obesity had been determined based on a waist circumference = 80 cm in women, according to the World Health Organization Asia-Pacific guidelines. Final diagnosis of sarcopenic obesity had been confirmed using dual-energy X-ray absorptiometry (DEXA).

Exclusion criteria

Exclusion criteria: Participants had been excluded if they had been medically advised against physical activity; had already been engaging in regular exercise more than three times per week for at least one month; had not met the diagnostic criteria for sarcopenic obesity (based on grip strength, SPPB score, and waist circumference); had been taking three or more medications for multiple chronic conditions; or had had systolic blood pressure =180 mmHg, diastolic pressure =110 mmHg, or had been classified as stage III hypertensive.

Design outcomes

Primary

MeasureTime frame
Inflammatory markers (RBP4, Adiponectin, IL-6, TNF-a)

Secondary

MeasureTime frame
Functional Fitness

Countries

Korea, Republic of

Contacts

Public ContactSung-Wook Chun

Pusan National University

onlylove8383@pusan.ac.kr+82-51-510-1845

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026