Comparison of wet and conventional polyp removal methods for 10–19 mm colorectal polyps

Randomized controlled trial comparing the efficacy and safety of wet endoscopic mucosal resection versus conventional endoscopic mucosal resection for 10–19 mm colorectal polyps

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011112

Enrollment

248

Registered

2025-11-06

Start date

2025-11-06

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : Name and Type of Intervention - Intervention Type: Procedure - Experimental Intervention: wet-EMR - Control Intervention: C-EMR Common Preparation and Pretreatment - Target Lesion

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: This study will include adult participants (aged 19 years or older) scheduled for endoscopic polypectomy after detection of 10–19 mm colorectal polyps during screening colonoscopy at Kosin University Gospel Hospital or other institutions. Inclusion criteria are as follows: - Presence of colorectal polyps measuring 10–19 mm confirmed by colonoscopy - Adults aged = 19 years - Individuals who have received a full explanation of the study purpose, procedures, potential risks, and benefits, and have providedvoluntary written informed consent - Individuals inadequate general condition to safely undergo a colonoscopic procedure under conscious sedation

Exclusion criteria

Exclusion criteria: Participants meeting any of the following criteria will be excluded from the study: - Presence of a submucosal tumor or a lesion suspected of invasive cancer - History of prior endoscopic resection or surgical intervention at the same site - Current use of anticoagulant or antiplatelet agents that cannot be discontinued prior to the procedure - Severe cardiovascular, respiratory, hepatic, or renal disease that makes endoscopic resection inappropriate or unsafe - Pregnant or breast feeding women - Individuals who cannot understand the study procedures or areunable to provide written informed consent - Individuals whom the investigator deems ineligible for participation due to safety or clinical concerns

Design outcomes

Primary

Measure	Time frame
R0 resection rate (complete histologic resection with negative lateral and deep margins)	—

Secondary

Measure	Time frame
En bloc resection rate;Procedure time;Delayed bleeding rate;Post-polypectomy coagulation syndrome (PPCS) incidence	—

Countries

Korea, Republic of

Contacts

Public ContactJae Hyun Kim

Kosin University Gospel Hospital

kjh8517@daum.net+82-51-990-6130

Outcome results