None listed
Conditions
Interventions
None listed
Sponsors
Wonkwang University, Gwangju Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Common Inclusion Criteria ? Male or female patients aged 19 years or older. ? Patients clinically and radiologically diagnosed with stroke, including ischemic stroke, hemorrhagic stroke, or subarachnoid hemorrhage (ICD-10 codes I60–I63) ? At least 3 months (90 days) have elapsed since the onset of stroke. ? Patients who are alert, able to communicate verbally, and capable of EEG measurement without expressive or cognitive impairment. ? Patients who understand the purpose of the study and voluntarily provide written informed consent to participate. 2) Inclusion Criteria for the Central Post-Stroke Neuropathic Pain (CPSP) Group ? Patients who developed new pain after stroke, characterized as persistent, burning, or tingling sensations, sometimes evoked by cold stimuli. ? The distribution of pain corresponds neuroanatomically to the lesion confirmed on neuroimaging. ? Neuropathic Pain Symptom Inventory (NPSI) total score = 20 3) Inclusion Criteria for the Non-CPSP (Control) Group ? Patients who meet all the common inclusion criteria but do not fulfill the CPSP group inclusion criteria.
Exclusion criteria
Exclusion criteria: 1) Patients with chronic pain existing prior to the onset of stroke. 2) Patients with other potential causes of pain, such as complex regional pain syndrome (CRPS), post-stroke shoulder pain, peripheral neuropathy, fibromyalgia, migraine, or other musculoskeletal disorders. • Supporting criteria: ? Pain that worsens or improves with specific movements or postures (e.g., shoulder pain aggravated by joint movement, knee osteoarthritis pain). ? Pain directly associated with inflammation or injury of local joints, muscles, or soft tissues (e.g., bursitis, tendinopathy, post-traumatic pain). ? Pain with a somatic segmental (dermatomal) distribution (e.g., lumbar radiculopathy, sciatica). ? Pain with typical peripheral neuropathic features, such as glove-and-stocking type sensory disturbances (e.g., diabetic neuropathy). ? Paroxysmal headache patterns (e.g., migraine, cluster headache). 3) Patients with neurological disorders other than stroke, such as Parkinson’s disease, dementia, multiple sclerosis, or epilepsy. 4) Patients diagnosed with severe psychiatric disorders, including major depressive disorder, schizophrenia, or anxiety disorders. 5) Individuals who are, in the investigator’s judgment, unable to participate in the clinical study due to medical or other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asymmetry features of power in major frequency bands (delta, theta, alpha, beta, gamma) during eyes-open (EO) and eyes-closed (EC) conditions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Delta/Alpha Ratio (DAR);(Delta + Theta)/(Alpha + Beta) Ratio (DTABR) | — |
Countries
Korea, Republic of
Contacts
Public ContactCheol-Hyun Kim
Wonkwang University, Gwangju Medical Center
Outcome results
None listed