None listed
Conditions
Interventions
None listed
Sponsors
Kyung Hee University Oriental Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults aged 19 years or older 2. Participants diagnosed for Hwabyung status using the Hwa-byung Diagnostic Interview Schedule (HBDIS) and the Hwa-byung Scale, according to the following criteria: 1) Hwabyung group: Participants who meet the diagnostic criteria of the HBDIS, score 30 or higher on the Hwa-byung Scale, and are classified into one of the five Hwabyung pattern identification subtypes (liver qi stagnation, liver fire flaming upward, disharmony between heart and kidney, qi and blood deficiency, or phlegm disturbing the gallbladder). 2) Control group: Participants who do not meet the diagnostic criteria of the HBDIS and score below 30 on the Hwa-byung Scale. 3. Participants who voluntarily decide to participate in this clinical study and provide written informed consent after receiving the subject information sheet. 4. Participants willing to comply with the clinical study protocol.
Exclusion criteria
Exclusion criteria: 1. Participants using a cardiac pacemaker. 2. Participants with current or past psychotic symptoms such as delusions or hallucinations. 3. Participants who have ever experienced manic episodes, hypomanic episodes, or mixed episodes. 4. Participants with current or past alcohol or substance abuse/dependence. 5. Participants with medical conditions that may affect Hwabyung-related symptoms. 6. Participants under treatment for liver cancer, liver cirrhosis, chronic renal failure, or congestive heart failure. 7. Participants with neurological or systemic diseases that may affect the central nervous system (e.g., neurocognitive disorders, cerebrovascular disease, Parkinson’s disease, Huntington’s disease, epilepsy, brain tumor, head trauma, hydrocephalus). 8. Pregnant or breastfeeding participants. 9. Participants currently enrolled in another clinical study or who have participated in another clinical study within 30 days prior to screening. 10. Participants deemed inappropriate for participation in this clinical study by the investigator for ethical or scientific reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalogram | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety;Emotional state assessments (K-BDI-II, K-STAI-YZ, STAXI, PHQ-15, ISI, SRI);Pulse wave measurement;Heart rate variability assessment | — |
Countries
Korea, Republic of
Contacts
Public ContactYunna Kim
Kyung Hee University Oriental Medical Center
Outcome results
None listed