A Pilot Study of a Symptom Cluster-based Intervention Program for Individuals with Subjective Cognitive Decline

A Pilot Study of a Symptom Cluster-based Intervention Program for Individuals with Subjective Cognitive Decline: Feasibility, Acceptability, and Preliminary Effectiveness

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0010981

Enrollment

Registered

2025-09-05

Start date

2025-11-03

Completion date

Unknown

Last updated

2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Behavioral : Symptom CLEAR Program (Symptom cluster-based education, activity, and relaxation [CLEAR] program) - Education: Six-session online educational video program. - Activity (Walking): Walking

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adults under 60 years of age Individuals scoring =24 on the Korean Mini-Mental State Examination (K-MMSE), indicating normal cognitive function Individuals scoring =7 on the Subjective Cognitive Decline Questionnaire (SCD-Q), indicating the presence of subjective cognitive decline Individuals with Patient-Reported Outcomes Measurement Information System–29 Profile (PROMIS-29) T-scores =50 in all five domains—anxiety, depression, fatigue, sleep disturbance, and pain—indicating a high symptom burden Individuals able to provide written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Individuals with a prior diagnosis of mild cognitive impairment (MCI) or dementia Individuals currently receiving pharmacological treatment for major psychiatric disorders (e.g., schizophrenia, bipolar disorder) Individuals with medical conditions that limit physical activity (e.g., cardiovascular, pulmonary, or other relevant diseases) Individuals who experience severe pain during walking or have back pain that interferes with occupational, social, or daily functioning Individuals who have participated in a cognitive-related clinical intervention program within the past six months Individuals unable to wear a smartwatch due to nickel allergy or other adverse reactions Individuals with communication or comprehension difficulties that interfere with study participation, or with difficulty adhering to study procedures

Design outcomes

Primary

Measure	Time frame
Health-related quality of life;Self-Efficacy;Resilience;Epigenetic age acceleration	—

Secondary

Measure	Time frame
Heart Rate Variability;step count	—

Countries

Korea, Republic of

Contacts

Public ContactYeseul Park

Pusan National University

s2eulmate@naver.com+82-51-510-8336

Outcome results