None listed
Conditions
Interventions
Drug : This study is designed as a prospective, randomized, double-blinded clinical trial involving a total of 70 obese adult patients scheduled for elective surgery. Participants who provide written
Sponsors
Chosun University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults aged between 20 and 65 years 2. Body Mass Index (BMI) = 25 kg/m² (including overweight and obese individuals) 3. Scheduled for elective surgery under general anesthesia 4. ASA Physical Status Classification I to III 5. Able to provide written informed consent after receiving a full explanation of the study
Exclusion criteria
Exclusion criteria: A. Emergency surgery B. History of resistance or hypersensitivity to benzodiazepines or other anesthetic agents C. Patients with acute angle-closure glaucoma D. Patients with neuromuscular disorders E. Patients with alcohol or drug dependence F. Patients with chronic renal failure or severe hepatic impairment (Child-Pugh Class C) G. Patients with genetic disorders such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to reach adequate anesthetic depth | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular adverse event rate (Hypotension: Systolic blood pressure 160 mmHg Bradycardia: Heart rate 110 beats per minute Arrhythmia or ECG abnormalities Oxygen saturation (SpO2) <92%) | — |
Countries
Korea, Republic of
Contacts
Public ContactSANG HUN KIM
Chosun University Hospital
Outcome results
None listed