None listed
Conditions
Interventions
Drug : This study is designed as a double blinded, randomized, prospective comparative clinical trial. After voluntarily signing the informed consent form, participants will be randomly assigned to on
Sponsors
Chosun University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A. Adults aged between 20 and 40 years who are scheduled to undergo general anesthesia for surgery B. Patients classified as American Society of Anesthesiologists (ASA) physical status I or II C. Patients with ASA physical status III whose underlying medical conditions are well-controlled and deemed suitable for general anesthesia based on preoperative anesthetic evaluation D. Patients who have voluntarily agreed to participate in this clinical study by providing written informed consent
Exclusion criteria
Exclusion criteria: A. Emergency surgery B. History of resistance or hypersensitivity to benzodiazepines or other anesthetic agents C. Patients with acute angle-closure glaucoma D. Patients with neuromuscular disorders E. Patients with alcohol or drug dependence F. Patients with chronic renal failure or severe hepatic impairment (Child-Pugh Class C) G. Patients with genetic disorders such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to reach adequate anesthetic depth | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular adverse event rate (Hypotension: Systolic blood pressure 160 mmHg Bradycardia: Heart rate 110 beats per minute Arrhythmia or ECG abnormalities Oxygen saturation (SpO2) <92%) | — |
Countries
Korea, Republic of
Contacts
Public ContactSANG HUN KIM
Chosun University Hospital
Outcome results
None listed