Whitening and anti-aging effect of the cosmetics containing Wharton's Jelly-derived mesenchymal stem cell-conditioned medium and mixed herbal extract

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0010899

Enrollment

Registered

2025-08-13

Start date

2024-12-30

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(cosmetics) : The active ingredients of the test substance include herbal complex extracts (Orostachys japonicus, Eclipta prostrata, Zizania latifolia, Portulaca oleracea, Artemisia princeps, Er

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy applicants aged 20 years or older and under 65 years. 2. Individuals showing signs of facial skin aging characteristics (mild pigmentation and wrinkles). 3. Volunteers who have received sufficient explanation about the purpose and content of the trial and have voluntarily signed a written consent form prior to the trial.

Exclusion criteria

Exclusion criteria: 1. If deemed unsuitable for study participation based on a visual assessment during the first visit. 2. Individuals with skin conditions such as sensitive skin (history of adverse reactions to local anesthetics, cosmetics, or medications), atopy, allergies, eczema, etc. 3. Individuals who have received treatment within the last 6 months involving laser, chemical peels, whitening procedures, etc. 4. Women who are pregnant or breastfeeding, or if pregnancy status is uncertain. 5. Individuals with a history of keloids. 6. Individuals expected to withdraw from the study or who are anticipated to be uncooperative during the study period. 7. Individuals currently participating in other clinical trials or who have participated in similar studies within the last 6 months. 8. Any other cases where the researchers believe that participation in the study is not feasible.

Design outcomes

Primary

Measure	Time frame
The difference in mean melanin values between the treatment group and the control group at the 8th week.	—

Secondary

Measure	Time frame
Erythema, Skin brightness, Wrinkles, Skin texture, Pores, Transepidermal water loss (TEWL), Subjective assessment by the study participant, Investigator's global assessment	—

Countries

Korea, Republic of

Contacts

Public ContactSoon-Hyo Kwon

Kyung Hee University Hospital at Gangdong

soonhyo17@hanmail.net+82-2-440-7329

Outcome results