None listed
Conditions
Interventions
Medical Device : The control group will undergo high-flux hemodialysis (HD) using a polysulfone (PS) dialysis membrane for 8 weeks, after which they will cross over to HD using the adsorptive NF dialy
Sponsors
Kyung Hee University Hospital at Gangdong
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Individuals who have voluntarily provided written informed consent to participate in the study 2) Adult men and women aged 18 years or older 3) Patients undergoing hemodialysis or hemodiafiltration three times per week due to chronic kidney disease 4) Patients with no residual renal function (total daily urine output less than 100 mL) 5) Patients receiving dialysis via an arteriovenous (AV) graft or fistula 6) Individuals who understand the details of the clinical trial, are cooperative with the study procedures, and are deemed capable of participating until study completion
Exclusion criteria
Exclusion criteria: 1) Pregnant or breastfeeding women 2) Individuals undergoing peritoneal dialysis in combination with hemodialysis 3) Individuals with poor compliance to hemodialysis treatment 4) Individuals with active medical conditions that preclude participation in the study 5) Individuals with a life expectancy of less than 6 months 6) Any other individuals deemed unsuitable for the study by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Protein bound uremic toxin removal rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective patient symptoms including post dialysis fatigue and itching ;White blood cell count, red blood cell count (hemoglobin, hematocrit), high-sensitivity C-reactive protein, total protein, albumin, electrolytes (Na, K, Cl, TCO2, Ca, P), PTH ;dialysate albumin loss | — |
Countries
Korea, Republic of
Contacts
Public ContactYoosun Joo
Kyung Hee University Hospital at Gangdong
Outcome results
None listed