None listed
Conditions
Interventions
Others(Bifidobacterium bifidum BGN4 Probiotics) : Based on the inclusion and exclusion criteria, a total of 60 eligible participants were selected and randomly assigned to one of two groups (n = 30 pe
Sponsors
Sookmyung Women's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Adults aged 19 to 64 years -Healthy adult men with a body fat percentage =20% and healthy adult women with a body fat percentage =28%
Exclusion criteria
Exclusion criteria: - Individuals with severe or chronic diseases such as malignant tumors, hypertension, diabetes, inflammatory bowel disease, renal or cardiac dysfunction, severe neurological disorders, psychiatric disorders, asthma, chronic obstructive pulmonary disease (COPD), or thyroid dysfunction (hyperthyroidism or hypothyroidism) - Individuals with liver disease, a history of liver-related conditions, or liver surgery - Individuals taking medications or supplements - Individuals who have taken any functional foods or medications intended to improve liver function or body fat composition within the past 4 weeks - Individuals who have taken prebiotics, probiotics, or synbiotics within the past 4 weeks - Individuals who have received antibiotic treatment within the past 3 months - Women who are pregnant, breastfeeding, or planning to become pregnant - Individuals with alcohol consumption >20 g/day for women (equivalent to ~2 glasses of beer or soju) or >30 g/day for men (~3 glasses of beer or soju) - Individuals with known allergies to probiotics or excipients - Individuals who have participated in a similar clinical trial within the past month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum hs-CRP | — |
Secondary
| Measure | Time frame |
|---|---|
| The relative abundance of Bifidobacterium bifidum BGN4;Serum fasting glucose;Serum fasting insulin;HOMA-IR;Serum Tumor Necrosis Factor a(TNFa);Serum zonulin;Serum Total antioxidant capacity(TAC);Serum Total cholesterol;Serum High-density lipoprotein(HDL) - cholesterol;Serum Low-density lipoprotein(LDL) - cholesterol;Serum Triglyceride(TG);Serum Aspartate aminotransferase(AST);Serum Alanine aminotransferase(ALT);Changes in fecal microbiota composition | — |
Countries
Korea, Republic of
Contacts
Public ContactJuwon Choi
Sookmyung Women's Hospital
Outcome results
None listed