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Underwater ESD-Single Clip vs Conventional ESD in large SCN

Comparisons of single clip traction with underwater endoscopic submucosal dissection and conventional endoscopic submucosal dissection for superficial colorectal neoplasias, randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0010761
Enrollment
120
Registered
2025-07-15
Start date
2025-07-04
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : single clip traction with underwater endoscopic submucosal dissection - after submucosal injection, partial circumferential submucosal incision around the superficial colorectal ne

Sponsors

Hallym University Medical Center-Kangnam
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients will be included in the study if they fulfill the following criteria: • Age of 19 years and older • able to provide written informed consent • patient with 20-50 mm sized superficial colorectal neoplasias scheduled endoscopic submucosal dissection

Exclusion criteria

Exclusion criteria: Patients will be excluded in the study if they fulfill the following criteria: • Age of <19 years • inable to provide written informed consent • patient with suspected deep invasive neoplasias, previously incomplete resection neoplasias, subepithelial lesion, protruded neoplasias, pedunculated neoplasias • located on ano-rectal juction, IC valve, appendicile orifice superficial colorectal neoplasias • inflammatory bowel disease patients, uninterrupted antithrombotic therapy patients, coagulopathy patients

Design outcomes

Primary

MeasureTime frame
dissection speed (mm2/min), which was defined as the calculated ratio of the resected specimen area (mm2) divided by the procedure time (minutes).

Secondary

MeasureTime frame
procedure time (measured as the time from the submucosal injection to complete removal of the superficial colorectal neoplasia based on endoscopic assessment);R0 resection;intra-procedural and post-procedural adverse effect(delayed bleeding, immediate perforation, delayed perforation)

Countries

Korea, Republic of

Contacts

Public ContactChang Kyo Oh

Hallym University Medical Center-Kangnam

ckdryekd@gmail.com+82-2-829-5120

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026