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A multicenter investigator prospective cohort study to analyze the association between the severity of periodontal disease and characteristics of the patient's immune status.

A multicenter investigator prospective cohort study to analyze the association between periodontal disease severity and host Immunologic Characteristics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0010638
Enrollment
120
Registered
2025-06-13
Start date
2025-08-18
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Yonsei University Health System, Dental Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients 19 years of age or older who are seen in the periodontal department Patients who are in maintenance therapy after active periodontal therapy

Exclusion criteria

Exclusion criteria: Factors that may affect the oral microbiome: antibiotics, smokers, and chemotherapy patients Uncontrolled systemic diseases In addition to the above, those with clinical findings deemed inappropriate for this study in the medical judgment of the principal investigator or the person in charge.

Design outcomes

Primary

MeasureTime frame
Discover immunologic patterns in patients based on stage—

Secondary

MeasureTime frame
eriodontal clinical indices in the full arch (assessment of probing depth, gingival recession, plaque index, gingival index, and bleeding on probing);IgM and IgG in GCF and saliva, B cells, plasma IgM and IgG;Serology test results—

Countries

Korea, Republic of

Contacts

Public ContactSeulbin Im

Yonsei University Health System, Dental Hospital

limsb@yuhs.ac+82-2-2228-2953

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026