None listed
Conditions
Interventions
None listed
Sponsors
The Catholic University of Korea, Seoul St. Mary's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients undergoing orthopedic surgery under general anesthesia Patients with Parkinson's disease undergoing orthopedic surgery under general anesthesia Patient's who signed the written and verbal informed consent
Exclusion criteria
Exclusion criteria: Patients who: - Take steroids or immunosuppressants that may affect the immune response - Have heart diseases, such as myocardial infarction or coronary artery disease, in addition to diabetes or hypertension - Have pulmonary diseases, such as asthma or chronic obstructive pulmonary disease (COPD) - Have liver disease with AST/ALT levels more than twice the normal range - Have a history of hypersensitivity reactions to inhalation anesthetics or propofol - Require vasopressors, such as dopamine or dobutamine, due to severe hypotension during surgery - Are undergoing cancer surgery - Require total intravenous anesthesia (TIVA) using propofol and remifentanil
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-6, IL-8, IL-10, IL-17, TNFa, IFN-? | — |
Secondary
| Measure | Time frame |
|---|---|
| CCL2, VEGF, S100B, HMGB-1 | — |
Countries
Korea, Republic of
Contacts
Public ContactJin Joo
The Catholic University of Korea, Seoul St. Mary's Hospital
Outcome results
None listed