None listed
Conditions
Interventions
Procedure/Surgery : If patients with non-ST-segment elevation myocardial infarction (NSTEMI) complicated by acute decompensated heart failure (AHF) fulfilling the eligibility criteria, participants wi
Sponsors
Chonnam National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age =19 years 2) NSTEMI 3) New-onset or worsening of dyspnea (New York Heart Association class =2) 4) Pulmonary congestion 5) Patient’s or guardian’s consent after understanding the study * NSTEMI is defined according to the current guideline and the Fourth Universal Definition of Myocardial Infarction. : Clinical evidence of acute myocardial ischemia and with detection of a rise and/or fall of cardiac troponin values with at least 1 value above the 99th percentile upper reference limit and at least of the following: ? Symptoms of myocardial ischemia ? New ischemic electrocardiographic changes (except for persistent ST-segment elevation in at least two contiguous leads) ? Development of pathological Q waves ? Imaging evidence of new loss of viable myocardium or new regional wall motion abnormality in a pattern consistent with an ischemic etiology
Exclusion criteria
Exclusion criteria: 1) Cardiogenic shock at initial presentation 2) ST-segment elevation myocardial infarction : ST-segment elevation =0.1 mV in at least 2 contiguous leads, or : New onset left bundle branch block : Posterior wall myocardial infarction 3) Refractory angina 4) Life threatening ventricular arrhythmias 5) Life expectancy 90 mmHg, and ? Pulmonary congestion on chest X-ray or increased left ventricular filling pressure by cardiac catheterization, and ? At least one criterion of organ dysfunction: altered mental status, cold/clammy skin, renal dysfunction (urine output 2.0 mmol/L)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A cumulative incidence rate of all-cause death, non-fatal myocardial infarction (MI), or hospitalization for heart failure (HF) | — |
Secondary
| Measure | Time frame |
|---|---|
| A cumulative incidence rate of all-cause death, non-fatal MI, or hospitalization for HF;All-cause death;Non-fatal MI;Hospitalization for HF;Cardiovascular death;Recurrent ischemia;All unplanned revascularization;Definite or probable stent thrombosis;Stroke;Major bleeding by Bleeding Academic Research Consortium;Acute kidney injury (AKI) and AKI requiring renal replacement therapy;In-hospital death rate from any cause;In-hospital death rate from cardiovascular cause | — |
Countries
Korea, Republic of
Contacts
Public ContactMin Chul Kim
Chonnam National University Hospital
Outcome results
None listed