None listed
Conditions
Interventions
None listed
Sponsors
Pusan National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Eligible participants are adult patients aged between 18 and 65 years who visit the neurology department of the hospital and meet the following criteria: A. Patients who meet the diagnostic criteria in the table below: Migraine with Aura A) At least two attacks fulfilling criteria B and C B) One or more of the following fully reversible aura symptoms: ? Visual ? Sensory ? Speech and/or language ? Motor ? Brainstem ? Retinal C) At least three of the following six characteristics: i. At least one aura symptom develops gradually over =5 minutes ii. Two or more aura symptoms occur in succession iii. Each individual aura symptom lasts between 5 and 60 minutes iv. At least one aura symptom is unilateral v. At least one aura symptom is positive vi. The aura is accompanied by or followed within 60 minutes by headache D) Not better accounted for by another ICHD-3 diagnosis Migraine without Aura A) At least five attacks fulfilling criteria B–D B) Headache attacks lasting 4 to 72 hours (when untreated or unsuccessfully treated) C) Headache has at least two of the following four characteristics: i. Unilateral location ii. Pulsating quality iii. Moderate or severe pain intensity iv. Aggravation by or causing avoidance of routine physical activity (e.g., walking or climbing stairs) D) During headache, at least one of the following: i. Nausea and/or vomiting ii. Photophobia and phonophobia E) Not better accounted for by another ICHD-3 diagnosis B. No evidence of other central nervous system abnormalities, and no abnormal findings suggestive of central lesions on brain imaging, neurological examination, or vestibular function tests. C. No use of prophylactic medication within 2 weeks prior to baseline. D. Provided written informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: Patients whose dizziness and headache are determined to be caused by an underlying central nervous system disorder or other identifiable medical conditions. Patients with clinically significant medical conditions (e.g., liver disease, kidney disease, malignancies) that, in the investigator’s judgment, would make study participation difficult. Patients who have difficulty understanding or expressing themselves, making it challenging to participate in the study. Patients who require continuous use of analgesics due to severe pain. Patients for whom the planned prophylactic medication is contraindicated based on specific safety criteria. Patients who, at the investigator’s discretion, are otherwise deemed unsuitable for study participation. Patients who do not provide informed consent. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache Frequency | — |
Secondary
| Measure | Time frame |
|---|---|
| Wong-Baker Pain Rating Scale (PRS);Headache Impact Test-6 (HIT-6), Migraine Disability Assessment Questionnaire (MIDAS);Visual Analogue Scale-Dizziness (VAS-D), Dizziness Handicap Inventory (DHI) , UCLA-Dizziness Questionnaire (UCLA-DQ) | — |
Countries
Korea, Republic of
Contacts
Public Contactseo young choi
Pusan National University Hospital
Outcome results
None listed