None listed
Conditions
Interventions
Dietary Supplement : Intervention Group (Experimental):
Participants in the intervention group consumed a functional food containing rice germ extract at a dose of 3 g once daily for a period of 3 mon
Sponsors
Kyung Hee University Global Campus
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Individuals aged between 50 and 79 years. ? Individuals whose handgrip strength in both hands falls below the standard reference values for their respective age and sex: 1) Age 50–59: = 42.0 kg for men, = 25.1 kg for women 2) Age 60–69: = 38.5 kg for men, = 24.1 kg for women 3) Age 70–79: = 33.2 kg for men, = 20.9 kg for women ? Individuals capable of performing normal physical activities and who have provided written informed consent to participate in the study. ? Individuals who are capable of oral intake.
Exclusion criteria
Exclusion criteria: ? Individuals whose handgrip strength exceeds the age-specific reference range. ? Individuals whose handgrip strength is below 28 kg for men or below 18 kg for women in both hands. ? Individuals with a BMI of 30 kg/m² or higher. ? Individuals who have musculoskeletal disorders (e.g., history of orthopedic surgery, current treatment for arthritis, or hip fractures), spinal disorders (e.g., spondylitis, ankylosing conditions), cognitive impairment (e.g., dementia, mild cognitive impairment), or neurological diseases (e.g., neuritis, stroke, cerebral hemorrhage) that hinder regular walking, daily activities, or exercise. ? Individuals currently taking psychiatric medications due to a diagnosed mental disorder. (However, those with insomnia receiving intermittent treatment or with adequately managed depression may participate at the discretion of the investigator.) ? Individuals with gastrointestinal disorders that may interfere with the consumption of the test product. ? Individuals with dietary restrictions due to diabetes, renal diseases (e.g., renal failure, dialysis), or hepatic diseases (e.g., cirrhosis, liver cancer), or those currently undergoing cancer treatment (e.g., surgery, chemotherapy, or radiation therapy). ? Individuals who have taken systemic corticosteroids (e.g., cortisol) or hormone therapies (e.g., testosterone, estrogen, androgen, growth hormone, or adrenal cortex hormones) within 4 weeks prior to the first visit. ? Individuals who have taken muscle-strength-related supplements (e.g., amino acids, creatine) or health functional foods associated with muscle strength improvement (e.g., calcium, vitamin D), or probiotics (more than 4 times per week) within 2 weeks prior to the first visit. (Participants taking calcium or vitamin D for more than 3 months without dosage change may be included.) ? Individuals with a history of alcohol abuse or those who chronically consume alcohol. * Defined as average daily alcohol intake exceeding 40 g (280 g/week) for men, or 20 g (140 g/week) for women. ? Individuals who have participated in other interventional clinical trials (including human studies) within 2 months prior to the first visit or who plan to participate in other interventional clinical trials during the study period. ? Individuals who are allergic or sensitive to any component of the investigational product (test or placebo). ? Individuals deemed inappropriate for participation by the investigator for other reasons (e.g., those who may cause disruption in the study environment).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in handgrip strength | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in isokinetic muscle strength | — |
Countries
Korea, Republic of
Contacts
Public ContactHee-Sook Lim
Kyung Hee University Global Campus
Outcome results
None listed