None listed
Conditions
Interventions
Medical Device : Among the xenografts, Bone-XB (MedPark, Busan, Korea), a bovine bone-derived xenograft, and Bio-Oss (Geistlich Pharma AG, Wolhusen, Switzerland), a bovine bone-derived xenograft, were
Sponsors
Yonsei University Health System, Dental Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Adults aged 18 to 65 years who visited the outpatient clinic of the Department of Integrated Dentistry, Yonsei University Dental Hospital - Patients who require extraction in the anterior or posterior region and are scheduled to have implant placement 4-6 months after extraction - Patients whose extraction socket shape is expected to be 3-wall or 4-wall after extraction - Patients with 2 adjacent teeth after extraction - Patients with no possibility of pregnancy
Exclusion criteria
Exclusion criteria: - Maxillary and mandibular 7th tooth (#17, #27, #37, #47) - Smokers who smoke more than 10 cigarettes a day - Those who have undergone soft tissue grafting surgery at the extraction site within the past 6 months - Those who have taken drugs that induce soft tissue hypertrophy (immunosuppressants, diuretics, antiepileptic drugs, etc.) or drugs that interfere with bone formation (adrenal cortex hormones, etc.) within 2 weeks of screening or are likely to take them during the clinical study - Those who have taken oral or injectable antirheumatic drugs - Patients with uncontrolled diabetes or hypertension - Those with skin diseases or lesions in the oral cavity (erosive lichen planus, stomatitis, ulcers, malignant tumors, etc.) - Those who have taken or are taking oral or injectable bisphosphonate osteoporosis treatment drugs for more than 3 months in the past (However, those who have stopped taking the medication for more than 3 months according to the AAOMS criteria or have a CTx level of 0.150 ng/ml or higher are not eligible to participate Possible) - Those suffering from systemic diseases related to bone metabolism (osteomyelitis, etc.) - Those with a history of tumor removal at the surgical site - Those with an allergy to collagen - Those with insufficient oral hygiene management skills - Those with periapical lesions observed in adjacent teeth - Those who have been diagnosed with malignant tumors within the past 5 years and have received radiotherapy or chemical treatment - Those with poor mental capacity (including disabled persons) - Pregnant women, lactating women, and minors - When the test subject withdraws consent - Other patients deemed inappropriate by the clinician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in ridge height and width | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of new bone area;Percentage of residual bone graft area;Percentage of connective tissue area | — |
Countries
Korea, Republic of
Contacts
Public ContactYiseul Choi
Yonsei University Health System, Dental Hospital
Outcome results
None listed