None listed
Conditions
Interventions
Drug : The perfusionist participating in the surgery mixes the cardioplegia solution according to the composition of the assigned group and administers it in the same manner for both groups. The compo
Sponsors
BUCHEON SEJONG HOSPITAL
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1-1) Adult inclusion criteria ? Adults aged 19 years or older ? Patients undergoing cardiac surgery using cardiopulmonary bypass ? Patients undergoing surgery under cardiac arrest using cardioplegia solution ? Patients who voluntarily agree to participate in this study and have provided informed consent 2-1) Pediatric inclusion criteria ? Patients under 7 years of age diagnosed with congenital heart defects who are undergoing open-heart surgery using cardiopulmonary bypass at our institution, with consent obtained from their legal guardian ? Target congenital heart defects: Atrial septal defect (ASD), Ventricular septal defect (VSD), Double outlet right ventricle (DORV), Tetralogy of Fallot (TOF), Partial anomalous pulmonary venous return (PAPVR), Total anomalous pulmonary venous return (TAPVR) ? Patients undergoing surgery under cardiac arrest using cardioplegia solution
Exclusion criteria
Exclusion criteria: 1-2) Adult exclusion criteria ? Aortic surgery ? Patients undergoing reoperation with a history of previous open-heart surgery ? Cases where surgery is performed under ventricular fibrillation or with the heart beating without using an aortic cross-clamp ? Emergency surgeries ? Patients requiring preoperative support with inotropes, mechanical ventilation, or mechanical assist devices ? Patients with active infections or infectious diseases classified as Category 1, 2, or 3 under Article 2, Paragraph 1 of the Infectious Disease Control and Prevention Act 2-2) Pediatric exclusion criteria ? Patients undergoing reoperation with a history of previous open-heart surgery ? Patients requiring preoperative intensive care unit treatment or emergency surgery ? Patients diagnosed with complex congenital heart defects involving multiple anomalies or single ventricle physiology ? Patients with congenital anomalies affecting organs other than the heart ? Patients clinically suspected or confirmed to have complex genetic syndromes ? Patients clinically suspected or confirmed to have active infections or infectious diseases classified as Category 1, 2, or 3 under Article 2, Paragraph 1 of the Infectious Disease Control and Prevention Act
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Troponin-T level | — |
Secondary
| Measure | Time frame |
|---|---|
| Lactate level;Vasoactive Inotropic score;Low cardiac output syndrome requiring mechanical circulatory support;In hospital mortality;MACCE(myocardial infarction, stroke, bleeding, acute kidney injury, infection) | — |
Countries
Korea, Republic of
Contacts
Public ContactHeemoon Lee
BUCHEON SEJONG HOSPITAL
Outcome results
None listed