None listed
Conditions
Interventions
Medical Device : 1. Intervention Details
(1) Pre-treatment Phase (4 weeks)
- A total of 30 patients with drug-resistant epilepsy who meet the inclusion criteria will be recruited through outpatient v
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A total of 30 drug-resistant epilepsy patients aged 18 or older with diverse characteristics, including epilepsy type, lesion location, seizure frequency, drug responsiveness, age, and gender, will be enrolled. Only patients with no safety concerns regarding EEG-fNIRS measurement and rTMS treatment and who provide informed consent will be included in the study.
Exclusion criteria
Exclusion criteria: Epilepsy patients will be excluded if they have safety concerns related to TMS stimulation, including the presence of a pacemaker, artificial heart valve, cerebral artery clip, vascular stent, metallic implants from surgery, artificial joint, implanted infusion pump, hearing aid, ECG electrodes, extensive body tattoos, or pregnancy. Additionally, patients with major neurological or psychiatric comorbidities (such as brain tumors or major depressive disorder), a history of severe head trauma or neurosurgery, or those who are pregnant or breastfeeding will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seizure frequency;Interictal Epileptiform Discharges | — |
Secondary
| Measure | Time frame |
|---|---|
| QOLIE-10(Quality of Life in Epilepsy-10) | — |
Countries
Korea, Republic of
Contacts
Public Contacthaeun Kim
Asan Medical Center
Outcome results
None listed