None listed
Conditions
Interventions
Medical Device : Functional neuroimaging using fNIRS/EEG will be conducted before and after acupuncture stimulation. Resting-state 5-min imaging will be acquired before and after acupuncture stimulati
Sponsors
Sangji University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Typically developing group -Typically developing children or adults aged 6 years or older without neurodevelopmental disabilities (matched with age and sex with ASD group) -Individuals who do not interfere with language communication, such as reading and writing, and who has obtained an informed consent after listening to the entire process of this study(or legal representative decided to participate and has given written consent) -Individuals without neurological and organic diseases that can cause neurodevelopmental disorders and cognitive decline 2)Autism Spectrum Disorder Group -Children and adults over 6 years of age diagnosed with autism spectrum disorder in pediatric psychiatry -Individuals who obtained informed consent after listening the entire process of the study or whose legal representative has decided to participate after listening to the entire process -Individuals with autism spectrum disorder whose symptoms are not better explained by other conditions or factors
Exclusion criteria
Exclusion criteria: 1) Typically developing group -Individuals with serious neuropsychiatric disorders -Individuals with a history of brain disorder -Individuals with severe internal medical conditions such as liver, heart and kidney diseases -Individuals with history of epilepsy, alcohol, drug addiction, or are on psychiatric medication -Individuals with genetic disorders associated with developmental disabilities -Individuals who are unable to conduct the study due to other causes according to the researcher's opinion 2) Autism Spectrum disorder group -Patients with cerebrovascular diseases such as cerebral hemorrhage and cerebral infarction -Individuals with mental retardation or severe cognitive decline due to other primary causes -Individuals with severe internal medical conditions such as liver, heart and kidney diseases -Individuals with epileptic history, alcohol or drug addiction -Individuals who take psychiatric medication due to comorbidities within one month of the change of medication -Individuals who are unable to conduct the study due to other causes according to the researcher's opinion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in brain activation and neuroimaging indices before and after genuine and sham acupuncture stimulation according to disease status | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in brain activation and functional neuroimaging indices between typically developing group and ASD participants;Brain activation areas and functional neuroimaging indices associated with autism symptoms (severity) | — |
Countries
Korea, Republic of
Contacts
Public ContactGye Jin Sim
Sangji University
Outcome results
None listed