None listed
Conditions
Interventions
Procedure/Surgery, Others : Patients with markedly reduced left ventricular systolic function on echocardiography and suspected ischemic cardiomyopathy are eligible for this study. To evaluate ischemi
Sponsors
Seoul National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Informed consent 2. Patients with LV ejection fraction=40% from cardiac MRI 3. Patients with multivessel disease in major epicardial coronary artery disease or their major branches (vessel size of 2.5 mm or more than 2.5mm) considering coronary revascularization
Exclusion criteria
Exclusion criteria: 1. Subjects with more than 50% transmural extent of infarction on GE-MRI in more than 25% of the dysfunctional myocardial segments 2. Suspicious of other cardiomyopathy (dilated cardiomyopathy, hypertrophic cardiomyopathy etc.) 3. Recent myocardial infarction within 4 weeks 4. Recent fatal arrythmia (VT or VF) within 4 weeks 5. Hemodynamically unstable state 6. Patients with complex coronary artery lesions, such as chronic total occlusions, in which complete revascularization is considered unfeasible 7. Patients for whom coronary artery bypass surgery is prioritized over coronary artery intervention 8. Patients with severe valvular heart disease requiring open heart surgery 9. History of coronary artery bypass surgery or valve surgery 10. Expected life expectancy of less than 1 year 11. Individuals considered ineligible for this study based on the investigator’s discretion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LV ejection fraction from GE-MRI | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the transmural extent of myocardial infarction from GE-MRI ;Number of improved dysfunctional myocardial segments from GE-MRI ;Changes in the LV chamber size from GE MRI ;LV ejection fraction from echocardiography ;Number of improved dysfunctional myocardial segments from echocardiography ;Changes in the LV chamber size change from echocardiography ;All-cause death ;Cardiovascular death ;Non-fatal myocardial infarction ;Unplanned revascularization ;Hospitalization for heart failure ;EuroQol 5-Dimension 5-Level Questionnaire;Brain natriuretic peptide (BNP or NT-Pro BNP) level ;NYHA Functional Class | — |
Countries
Korea, Republic of
Contacts
Public ContactDoyeon Hwang
Seoul National University Hospital
Outcome results
None listed